Study the host response and mechanism of action to infection in various infectious diseases including TB, malaria, viral infection and other public health diseases.
Identify the interacting signaling pathways and the key proteins in host cells in responding to pathogens and other environmental challenges.
Isolate and establish primary immuno-cell culture based on the special properties of various types of immune cells.
In collaboration with assay development group to identify biochemical or cellular assays to screen for cmpds improving host immune system against challenges.
Develop additional assays for hit validation and triage.
Work closely with medichem group to examine in vitro efficacy of cmds as a guidance to SAR.
Responsibilities may vary depending on the training background and experience.
PhD degree in immunology, cell biology, molecular biology or the related biological sciences with 0-6 year experience.
In depth understanding of and working experience with human innate and/or adaptive immune-regulation.
Familiar with immune cell types and their properties/markers and techniques in the field.
Good team player, excellent collaboration and communication skills.
Oral and written skill of English in scientific communication. Scientific integrity is a must; candidate should be professional in maintaining lab notebooks and electronic files.