旭华（上海）生物研发中心有限公司

PharMab, Inc., located in Zhangjiang HighTech Park of Pudong, Shanghai, China

PharMab positions itself as the leading company in China in developing biopharmaceuticals using genetic engineering techniques. Equipped with the most advanced instruments and laboratory facility, the company has established a unique technology platform stemming from numerous years of experience of its technical team in research and development of biotech products. This technology platform could streamline the production and development of therapeutic monoclonal antibody products and their derivatives.

Biotechnology will become the premier industry in the 21st century. It will be the focal point of global race in technology and economy. The bio-economy, as it builds around the biotech industry, will play the leading role in the growth of global economy in many years to come. The goal of PharMab is to become a leader China in the development of proprietary biotech products using its unique technology platform, and to compete in the international market, as China is elevating its presence and strengthen its competitiveness in the global biotech community.

Technology Platform

1. Antibody Technology Platform

With its unique and powerful techniques in immunization, fusion, and functional screening, PharMab is able to effectively develop monoclonal antibodies with high specificity and affinity against desired disease target molecules. It could subsequently humanize the antibody candidates for therapeutic development.

2. Protein Expression and Purification Platform

With its unique protein expression techniques, PharMab is able to create cell lines derived from mammalian host cells, including Chinese Hamster Ovary (CHO) and murine myeloma cells, to express the target genes at high secretion levels. Paired with its proprietary medium formulation and cell culture techniques, PharMab is also able to grow these cells in suspension culture to produce high levels of protein (including monoclonal antibody) products. In addition, PharMab also has the capability to purify these protein products to high degree of purity using chromatographic methods.