Key Responsibilities:
Study Pathology & Interpretation
1.Perform microscopic examination of tissues from toxicology, pharmacology, investigative studies.
2.Distinguish background, incidental, test article–related findings.
3.Provide pathology peer review when needed.
4.Train mentjunipathologists, necropsy technicians, pathology scientists.
Study Design & Planning
1.Contribute to the design of toxicology studies, including tissue collection plans special stains biomarkers.
2.Work closely with toxicologists pharmacologists to ensure appropriate histopathological endpoints are defined.
3.Adviseon species selection, dose levels, study duration from a pathology perspective.
Data Recording & Reporting
1.Record observations in GLP-compliant pathology data systems (e.g., Provantis, PathData) if applicable.
2.Review and/Authpathology reports.
3.Integrate histopathology results with clinical pathology, toxicokinetic, biomarker data to support mechanistic interpretation.
4.Ensure data quality integrity.
Advanced / Investigative Pathology
1.Collaborate with pathobiology, molecular toxicology, imaging teams to explore drug-induced changes.
2.Participate in tissue-based biomarker discovery translational pathology efforts.
3.Apply special stains, immunohistochemistry (IHC), in situ hybridization (ISH), digital pathology tools to elucidate mechanisms of toxicity.
Key Interfaces
4.Internal: Toxicologists, study directors, clinical pathologists, safety pharmacologists, bioanalysts, regulatory affairs, data scientists.
5.External: Contract Researchganizations (CROs), regulatory agencies, industry pathology networks.
Qualifications & Experience
1.Education；BS, MS, Ph.D in Veterinary Science related fields
2.Experience：3–10 years in toxicologic preclinical pathology (pharma, CRO, regulatory). Experience with GLP-compliant studies preferred.
3.Expertise ：Broad background in toxicologic histopathology, pathology peer review, mechanistic pathology.
4.Skills： Excellent microscopy, interpretation, reporting skills; familiarity with digital pathology tools.
5.Knowledge：GLP, OECD, ICH M3(R2), SEND data standards, FDA/EMA preclinical safety guidelines.
6.Soft Skills ：Analytical thinking, attention to detail, strong communication, teamwork, documentation discipline.
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